Our laboratory is interested in understanding how neurotransmission is regulated with the ultimate goal of identifying and validating novel therapeutic targets with which to treat psychiatric disorders. We utilize electrophysiology, fiber photometry, and behavioral pharmacology techniques to study rodent brain circuits that are homologous to those dysregulated in mental health disorders like schizophrenia and autism spectrum disorder. We also use pharmacological tools and genetically modified mice to determine how modulation of specific G-protein coupled receptors can regulate these circuits.